Research progress of microfluidic chips in age-related macular degeneration
10.3980/j.issn.1672-5123.2023.11.12
- VernacularTitle:微流控芯片在年龄相关性黄斑变性中的研究进展
- Author:
Bi-Qian LIN
1
;
Dong-Cheng LIU
1
;
Bo QIN
1
Author Information
1. The Second Clinical Medical College of Jinan University, Shenzhen 518000, Guangdong Province, China
- Publication Type:Journal Article
- Keywords:
microfluidic chips;
age-related macular degeneration;
mechanism research;
drug evaluation;
clinical translation
- From:
International Eye Science
2023;23(11):1831-1834
- CountryChina
- Language:Chinese
-
Abstract:
Age-related macular degeneration(ARMD)is the primary cause of severe visual impairment and blindness in people over 60 years old. With the aging of the global population, the incidence of the disease is also rising year by year. However, the pathogenesis and treatment strategy of ARMD need to be further explored. As a cutting-edge science and technology, microfluidic chips can build a comprehensive microsystem that simulates the condition and function of human tissues and organs, which has the advantages of less sample consumption and short analysis time. In recent years, many studies have confirmed that microfluidic chips can bring brand new technology solutions to the basic and clinical research of ARMD. This article will discuss and review the application progress of microfluidic chips in the areas of ARMD mechanism research, drug evaluation and clinical translation, providing a theoretical reference for further research on the diagnosis and treatment of ARMD.
