Changes and effects of lymphatic vessels and lymphatic endothelial cells in lymph node metastasis of esophageal cancer
- VernacularTitle:淋巴管与淋巴管内皮细胞在食管癌淋巴转移过程中的作用及变化
- Author:
Jiayi GUO
1
,
2
;
Muming ALIMUJIANG
1
,
2
;
Awut EDRIS
1
,
2
;
Haiping ZHANG
1
,
2
;
Liwei ZHAGN
1
,
2
Author Information
1. Department of Thoracic Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, P. R. China ;
2. State Key Laboratory of Xinjiang Medical University, Urumqi, 830054, P. R. China
- Publication Type:Journal Article
- Keywords:
Esophageal cancer;
lymphatic metastasis;
lymphatic endothelial cell;
tumor-related lymph vessels;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2023;30(05):766-772
- CountryChina
- Language:Chinese
-
Abstract:
The lymphatic system is the main way of tumor metastasis and diffusion. Esophageal cancer is one of the typical cancers that are prone to metastasis through the lymphatic system. At present, an increasing number of studies show that the interaction between tumor cells and lymphatic endothelial cells is the first step in tumor lymphatic metastasis, but the underlying molecular mechanism is unclear. This article reviews the role and changes of tumor-related lymphatic vessels and lymphatic endothelial cells in the process of tumor lymphatic metastasis, which lays a foundation for further study of the specific molecular mechanism of esophageal cancer lymphatic metastasis and provides a new treatment direction for esophageal cancer patients.
