Clinical molecular diagnosis of breast and female reproductive system tumors
10.3760/cma.j.cn114452-20221127-00703
- VernacularTitle:乳腺及女性生殖系统肿瘤的临床分子诊断应用
- Author:
Qian WU
1
;
Jingwei WANG
;
Hongyun ZHENG
;
Yongqing TONG
Author Information
1. 武汉大学人民医院检验医学中心,武汉 430060
- Keywords:
Urogenital neoplasms;
Molecular diagnostic techniques;
Ovarian neoplasms;
Cervical neoplasms;
Breast neoplasms;
Endometrial neoplasms
- From:
Chinese Journal of Laboratory Medicine
2023;46(4):334-340
- CountryChina
- Language:Chinese
-
Abstract:
The gynecological tumours such as Breast cancer or female reproductive system tumors are a serious threat to female health. With the development of molecular diagnosis, the genomic changes of gynecological tumours have been revealed continuously, and the diagnosis and treatment modes of tumors have gradually changed. The detection of molecular targets which potentially participated in the transformation or progress of disease has become an important section of the management of female reproductive tumors, and accurate identification of molecular targets of tumors plays an important role in disease diagnosis, monitoring of metastasis, prediction of recurrence and treatment. This review briefly discusses the risk assessment, molecular typing, targeted therapy, toxic and side effects, and prognosis evaluation of breast and female reproductive system tumors by molecular diagnosis.