Research progress on use of tissue equivalent filler in postmastectomy radiation therapy of breast cancer
10.3760/cma.j.cn113030-20210926-00371
- VernacularTitle:乳腺癌根治术后放疗中组织等效填充物使用的研究进展
- Author:
Li CHEN
1
;
Jianjun QIAN
;
Ye TIAN
Author Information
1. 苏州大学附属第二医院放射治疗科,苏州大学放射肿瘤治疗学研究所,苏州市肿瘤放射治疗学重点实验室,苏州 215004
- Keywords:
Breast neoplasms;
Post-mastectomy radiotherapy;
Tissue-equivalent material;
Skin toxicity, acute / late;
Local control rate
- From:
Chinese Journal of Radiation Oncology
2023;32(2):184-188
- CountryChina
- Language:Chinese
-
Abstract:
Although the use of postmastectomy radiation therapy (PMRT) has been proven to bring survival benefit to breast cancer patients, the use of chest wall tissue equivalent filler (bolus) remains controversial. In recent years, a large number of studies have shown that the use of bolus in PMRT does not significantly improve the local control rate, while it can significantly increase the acute skin toxicity, and even leads to more frequent and longer treatment interruption. Existing retrospective studies have indicated that for breast cancer patients undergoing mastectomy and systemic therapy, if there is no skin invasion, it is recommended not to routinely use bolus during radiotherapy. However, higher-level clinical studies are needed for further confirmation.