Electroconvulsive therapy in schizophrenia: a review of neuroimaging studies
10.3760/cma.j.cn371468-20231010-00601
- VernacularTitle:精神分裂症电休克治疗效应的神经影像学进展
- Author:
Yuru LING
1
;
Xiangrong ZHANG
Author Information
1. 南京医科大学附属脑科医院，南京 210000
- Keywords:
Schizophrenia;
Electroconvulsive therapy;
Magnetic resonance imaging;
Functional connectivity
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2023;32(4):373-378
- CountryChina
- Language:Chinese
-
Abstract:
Electroconvulsive therapy (ECT) is a physical therapy method with rapid onset and remarkable effect for schizophrenia(SZ). It is widely used in patients with agitated impulses, stupor and refractory patients with poor drug treatment effect. The neurophysiological mechanism of ECT effect has not been elucidated. In the past decade, the magnetic resonance imaging (MRI) studies of ECT for SZ have been gradually reported in domestic and international journal, involving magnetic resonance spectroscopy, structural state and resting state analysis, preliminary findings suggest that there may be a correlation between ECT efficacy and structural and functional brain changes, mainly involving morphological changes in brain regions such as the thalamus, hippocampus, insula and left medial prefrontal lobe, as well as functional changes in core resting state networks, particularly the dorsal frontoparietal network, default network and limbic network. More research and exploration are needed in the future to provide valuable clues to further explore the therapeutic mechanism of ECT treatment.
