Research progress of perineural invasion in gallbladder cancer
10.3760/cma.j.cn115610-20230606-00266
- VernacularTitle:胆囊癌神经浸润研究进展
- Author:
Jianjun LEI
1
;
Jian ZHANG
;
Dong ZHANG
;
Rui ZHANG
;
Chen CHEN
;
Zhimin GENG
Author Information
1. 西安交通大学第一附属医院肝胆外科，西安 710061
- Keywords:
Biliary tract neoplasms;
Perineural invasion;
Mechanism;
Prognosis;
Research progress
- From:
Chinese Journal of Digestive Surgery
2023;22(7):933-937
- CountryChina
- Language:Chinese
-
Abstract:
As a special mode of tumor metastasis, perineural invasion has been paid more and more attention. It is closely related to prognosis, recurrence and metastasis of tumor after surgery. As the most common malignancy of the biliary tract, perineural invasion is also an inde-pendent prognostic risk factor for gallbladder cancer due to its anatomical location, lymphatic reflux, blood perfusion and innervation. However, there are few studies on perineural invasion in gallbla-dder cancer, especially on its mechanism. By analyzing the general situation and recent progress of perineural invasion in gallbladder cancer, the authors mainly introduce the perineural invasion mechanism, perineural invasion rate of gallbladder cancer, relationship between perineural invasion and the clinical pathologic characteristic, the correlation with the prognosis, relationship with surgi-cal procedures and postoperative adjuvant therapy.
