Research progress in pathology and imaging of intraductal papillary mucinous neoplasms of the pancreas
10.3760/cma.j.cn121382-20211208-00314
- VernacularTitle:胰腺导管内乳头状黏液性肿瘤的病理学及影像学进展
- Author:
Lihui ZHAO
1
;
Hailing WANG
Author Information
1. 天津医科大学肿瘤医院超声诊疗科，国家肿瘤临床医学研究中心，天津市 "肿瘤防治" 重点实验室，天津市恶性肿瘤临床医学研究中心，天津 300060
- Keywords:
Pancreatic neoplasms;
Intraductal papillary mucinous neoplasm;
Pathology;
Diagnosis
- From:
International Journal of Biomedical Engineering
2022;45(3):274-279
- CountryChina
- Language:Chinese
-
Abstract:
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a cystic tumor of the pancreas with some malignant potential. According to the degree of pancreatic duct expansion and the location of the tumor, it can be divided into main-duct type, branch-duct type, and mixed type. According to the degree of atypia, it can be classified as low-grade dysplasia, high-grade dysplasia, or invasive IPMN. According to histological morphology and immunohistochemistry, there are four subtypes: gastric type, intestinal type, pancreaticobiliary type, and eosinophilic type. Ultrasound is commonly used in screening and follow-up, while CT, MRI/MRCP, and EUS can identify IPMN with high-risk and anxiety characteristics, which are valuable in determining the timing of surgery and patient status. Imaging omics is highly accurate in assessing the degree of dysplasia and can be used to identify people at high risk of malignant transformation. In this article, the clinical manifestations, pathology, and imaging features of IPMN are reviewed in the light of the relevant guidelines and literature in recent years, in order to deepen our understanding of IPMN and thus improve the accuracy of imaging diagnosis.
