Progress of biomarkers related to neonatal necrotizing enterocolitis
10.3760/cma.j.issn.1673-4408.2023.04.004
- VernacularTitle:新生儿坏死性小肠结肠炎相关生物标志物的研究进展
- Author:
Dan QIAO
1
;
Fei BEI
Author Information
1. 上海交通大学医学院附属上海儿童医学中心新生儿科 200127
- Keywords:
Infant;
Neoborn;
Necrotizing enterocolitis;
Biomarkers
- From:
International Journal of Pediatrics
2023;50(4):234-238
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal necrotizing enterocolitis(NEC)is a life-threatening intestinal disease in newborns, and early identification of NEC is a major clinical challenge.Although clinical manifestations, routine laboratory tests and imaging examinations are essential for NEC, more and more studies in recent years based on the understanding of the pathogenesis of NEC have reported that NEC-related biomarkers such as fatty acid-binding proteins, cytokines, and intestinal flora have potential value in its prediction, early diagnosis, severity assessment and prognosis.This review will discuss the biomarkers related to NEC that have been studied in recent years from three aspects: blood, urine and feces, so as to guide clinical application.
