Progress of gene alterations and molecular typing of peripheral T-cell lymphoma
10.3760/cma.j.cn115356-20220216-00043
- VernacularTitle:外周T细胞淋巴瘤基因改变及分子分型研究进展
- Author:
Yue XU
1
;
Qingyuan ZHANG
;
Shu ZHAO
Author Information
1. 哈尔滨医科大学附属肿瘤医院内三科，哈尔滨 150000
- Keywords:
Peripheral T-cell lymphoma;
Gene alteration;
Molecular typing;
Molecular targeted therapy
- From:
Journal of Leukemia & Lymphoma
2023;32(5):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Peripheral T-cell lymphoma (PTCL) is a group of heterogeneous malignant tumors with poor prognosis, with a lack of standard treatment regimen and poor efficacy of traditional chemotherapy. Therefore, finding new and more effective therapeutic targets to improve the efficacy of PTCL is an urgent clinical problem. In recent years, as the exploration of PTCL at the genetic and molecular levels has intensified, novel therapeutic targets based on gene alterations and molecular typing have been identified. This article summarizes the research progress of main gene alterations and molecular typing of PTCL in recent years.
