Progress of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 in hematological malignancies
10.3760/cma.j.cn115356-20220118-00019
- VernacularTitle:长链非编码RNA肺腺癌转移相关转录本1在血液系统肿瘤中的研究进展
- Author:
Min SHI
1
;
Wenjing WANG
;
Yuanyuan ZHANG
;
Yongjun LI
Author Information
1. 河北医科大学第二医院检验科,石家庄 050000
- Keywords:
Hematologic neoplasms;
Long non-coding RNA;
Metastasis-associated lung adenocarcinoma transcript 1
- From:
Journal of Leukemia & Lymphoma
2022;31(12):759-762
- CountryChina
- Language:Chinese
-
Abstract:
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) plays an important role in the development of various tumors. Recent studies have shown that MALAT1 is highly expressed in hematological tumors and can participate in development, progression and prognosis of hematological tumors at transcriptional and post-transcriptional levels as a competitive endogenous RNA. Therefore, MALAT1 might be a novel marker as a valuable basis for the diagnosis, treatment and prognosis evaluation of hematological tumors.