Progress based on the clinical translation of the anxiolytic effects of oxytocin
10.11886/scjsws20221227001
- VernacularTitle:基于催产素的抗焦虑作用向临床转化的研究进展
- Author:
Ping CHEN
1
;
Lu WANG
1
;
Xinhua SHEN
1
Author Information
1. The Third People's Hospital of Huzhou City， Huzhou 313000， China
- Publication Type:Review
- Keywords:
Oxytocin;
Anxiety;
Clinical translation
- From:
Sichuan Mental Health
2023;36(3):271-276
- CountryChina
- Language:Chinese
-
Abstract:
The etiology and pathogenesis of anxiety disorders were still unknown with limited progress in treatment， and had a low cure rate and a high relapse rate. Oxytocin has attracted attention in recent years due to its anxiolytic effect， especially validated in animal experiments， but there are few studies in humans. Therefore， the purpose of this paper is to illustrate the pathological mechanism of anxiety through review researches on oxytocin and anxiety in recent years. Anxiety disorder is one of the most common mental disorder， and the imbalance of neurotransmitters is one of the pathogenesis. As a common neurotransmitter in the brain， oxytocin participated in the process of anxiety regulation. The purpose of this article is to summarize the research related to oxytocin to explore its possible mechanism of regulating anxiety， and to provide new ideas for diagnosis and treatment of anxiety disorders in combination with the clinical findings. ［Funded by Zhejiang Health Science and Technology Plan （number， 2022KY367）］.
