Survey of prevalence of hepatitis C in people aged 1-69 years in Henan Province, 2020.
10.3760/cma.j.cn112338-20220815-00711
- VernacularTitle:河南省2020年1~69岁人群丙型肝炎流行状况调查
- Author:
Jie LI
1
;
Xiao Yu JI
1
;
Jie GENG
1
;
Ning LI
1
;
Guo Long ZHANG
1
;
Dong Yang ZHAO
1
;
Yang LIU
1
;
Yu Gang NIE
1
;
Pan Ying FAN
1
Author Information
1. Institute for Prevention and Control of STD/AIDS, Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China.
- Publication Type:Journal Article
- MeSH:
Female;
Humans;
Male;
Coinfection;
Genotype;
Hepacivirus/genetics*;
Hepatitis C/epidemiology*;
Hepatitis C Antibodies/genetics*;
Prevalence;
RNA, Viral/genetics*;
Surveys and Questionnaires;
Infant;
Child, Preschool;
Child;
Adolescent;
Young Adult;
Adult;
Middle Aged;
Aged
- From:
Chinese Journal of Epidemiology
2023;44(7):1114-1118
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To understand the infection status and epidemiological characteristics of hepatitis C in people aged 1-69 years in Henan Province in 2020. Methods: The estimated sample size was 5 827. From August to December 2020, multistage sampling was used to select 8 counties (districts) in Henan, and two survey sites were selected in each county (district), and a questionnaire survey was conducted in local people aged 1-69 years, blood samples were collected from them for anti-HCV, HCV RNA and genotype detections. Results: A total of 5 165 people aged 1-69 years completed the questionnaire survey. Men accounted for 44.76% (2 312/5 165), women accounted for 55.24% (2 853/5 165). In the people aged 1-69 years, the overall prevalence rates of anti-HCV and HCV RNA were 0.69% (95%CI: 0.68%-0.70%) and 0.20% (95%CI: 0.19%-0.21%) respectively. The prevalence rates of anti-HCV and HCV RNA were 0.48% (95%CI: 0.46%-0.50%), 0.09% (95%CI: 0.08%-0.10%) in men and 0.86% (95%CI: 0.85%-0.87%), 0.30% (95%CI: 0.28%-0.32%) in women. The prevalence rates of anti-HCV and HCV RNA increased with age. The prevalence rates of anti-HCV and HCV RNA were 0.87% (95%CI: 0.86%-0.88%), 0.28% (95%CI: 0.26%-0.30%) in urban residents and 0.53% (95%CI: 0.51%-0.55%), 0.14% (95%CI: 0.13%-0.15%) in rural residents. The genotyping results of 10 HCV RNA positive samples ware genotype 1b (4/10), genotype 2 (3/10), genotype 1b/3 (1/10), genotype 1b/3/6 (1/10) and genotype 2/6 (1/10). Conclusions: The prevalence of hepatitis C was low in Henan in 2020. It is necessary to strengthen hepatitis C surveillance in people aged 40 years and above. The major HCV genotypes were 1b and 2, and mixed genotype infection existed.
