Performance of screening of contacts of COVID-19 cases in same flight.
10.3760/cma.j.cn112338-20230228-00112
- VernacularTitle:新型冠状病毒感染者航班同乘风险人员排查效果分析
- Author:
Dan LI
1
;
Ying QIN
1
;
Si Meng FAN
1
;
Zhi Bin PENG
1
;
Hui GE
2
;
Zhao Rui CHANG
1
;
Rui ZHANG
2
;
Xiao Kun YANG
1
;
Hong Ting ZHAO
1
;
Jian Dong ZHENG
1
;
Shi Cheng YU
3
;
Hui WANG
4
;
Jun YAN
5
;
Zhong Jie LI
6
Author Information
1. Division of Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
2. Information Center, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
3. Office for Epidemiology, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
4. National Bureau for Disease Control and Prevention, Beijing 100088, China.
5. Chinese Center for Disease Control and Prevention, Beijing 102206, China.
6. National Bureau for Disease Control and Prevention, Beijing 100088, China Chinese Center for Disease Control and Prevention, Beijing 102206, China.
- Publication Type:Journal Article
- MeSH:
Humans;
COVID-19;
Retrospective Studies;
SARS-CoV-2;
China;
Nucleic Acids
- From:
Chinese Journal of Epidemiology
2023;44(5):713-719
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To understand the performance of 2019-nCoV nucleic acid detection in screening of contacts of COVID-19 cases in same flights and provide evidence for the effective screening of persons at high risk for the infection in domestic flights. Methods: The information of passengers who took same domestic flights with COVID-19 cases in China from April 1, 2020 to April 30, 2022 were retrospectively collected,and χ2 test was used to analyze positive nucleic acid detection rates in the passengers in different times before the onsets of the index cases, in different seat rows and in epidemic periods of different 2019-nCoV variants. Results: During the study period, a total of 433 index cases were identified among 23 548 passengers in 370 flights. Subsequently, 72 positive cases of 2019-nCoV nucleic acid were detected in the passengers, in whom 57 were accompanying persons of the index cases. Further analysis of the another 15 passengers who tested positive for the nucleic acid showed that 86.67% of them had onsets or positive detections within 3 days after the diagnosis of the index cases, and the boarding times were all within 4 days before the onsets of the index cases. The positive detection rate in the passengers who seated in first three rows before and after the index cases was 0.15% (95%CI: 0.08%-0.27%), significantly higher than in the passengers in other rows (0.04%, 95%CI: 0.02%-0.10%, P=0.007),and there was no significant difference in the positive detection rate among the passengers in each of the 3 rows before and after the index cases (P=0.577). No significant differences were found in the positive detection rate in the passengers, except the accompanying persons, among the epidemics caused by different 2019-nCoV variants (P=0.565). During the Omicron epidemic period, all the positive detections in the passengers, except the accompanying persons, were within 3 days before the onset of the index cases. Conclusions: The screening test of 2019-nCoV nucleic acid can be conducted in the passengers took the same flights within 4 days before the onsets of the index cases on board. Passengers who seated within 3 rows from the index cases can considered as the close contacts at high risk for 2019-nCoV, for whom screening should be conducted first and special managements are needed. The passengers in other rows can be classified as general risk persons for screening and management.
