Research Progress on Estimation of Postmortem Interval Using mRNA and ncRNA.
10.12116/j.issn.1004-5619.2020.06.011
- Author:
Ye Hui LÜ
1
;
Zhuo Qun WANG
1
;
Yi Jiu CHEN
2
;
Long CHEN
3
Author Information
1. School of Basic Medical Sciences, Shanghai University of Medicine & Health Sciences, Shanghai 201318, China.
2. Shanghai Key Laboratory of Forensic Medicine, Key Laboratory of Forensic Science, Ministry of Justice, Shanghai Forensic Service Platform, Academy of Forensic Science, Shanghai 200063, China.
3. Department of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
- Publication Type:Journal Article
- Keywords:
forensic pathology;
estimation of postmortem interval;
messenger RNA (mRNA);
non-coding RNA (ncRNA);
review
- MeSH:
Autopsy;
Forensic Pathology;
Humans;
Postmortem Changes;
RNA, Messenger/genetics*;
RNA, Untranslated;
Time Factors
- From:
Journal of Forensic Medicine
2020;36(6):807-809
- CountryChina
- Language:Chinese
-
Abstract:
Postmortem interval (PMI) estimation has always been an important and difficult issue in the field of forensic pathology. In recent years, research progress on the estimation of PMI using RNA specific variation patterns after death has been made by researchers at home and aboard. This paper summarizes the specific application methods of messenger RNA and non-coding RNA for PMI estimation based on the literatures and discusses the existing problems and development trends, in order to provide technical reference for related studies and estimation practice.