Clinical characteristics of plastic bronchitis and risk factors for recurrence in children.
10.7499/j.issn.1008-8830.2211122
- Author:
Xiao-Yin TIAN
1
;
Guang-Li ZHANG
1
;
Chong-Jie WANG
1
;
Rui-Xue GU
1
;
Yuan-Yuan LI
1
;
Qin-Yuan LI
1
;
Jian LUO
1
;
Zheng-Xiu LUO
1
Author Information
1. Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University/National Clinical Research Center for Child Health and Disorders/Ministry of Education Key Laboratory of Child Development and Disorders/Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.
- Publication Type:Journal Article
- Keywords:
Bronchoscopy;
Child;
Clinical characteristic;
Plastic bronchitis;
Recurrence
- MeSH:
Female;
Male;
Child;
Humans;
Child, Preschool;
Multiple Organ Failure;
Retrospective Studies;
Bronchitis/etiology*;
Dyspnea;
Pleural Effusion;
Pulmonary Atelectasis;
Plastics;
Respiratory Insufficiency
- From:
Chinese Journal of Contemporary Pediatrics
2023;25(6):626-632
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVES:To study the clinical characteristics of plastic bronchitis (PB) in children and investigate the the risk factors for recurrence of PB.
METHODS:This was a retrospective analysis of medical data of children with PB who were hospitalized in Children's Hospital of Chongqing Medical University from January 2012 to July 2022. The children were divided into a single occurrence of PB group and a recurrent PB group and the risk factors for recurrence of PB were analyzed.
RESULTS:A total of 107 children with PB were included, including 61 males (57.0%) and 46 females (43.0%), with a median age of 5.0 years, and 78 cases (72.9%) were over 3 years old. All the children had cough, 96 children (89.7%) had fever, with high fever in 90 children. Seventy-three children (68.2%) had shortness of breath, and 64 children (59.8%) had respiratory failure. Sixty-six children (61.7%) had atelectasis and 52 children (48.6%) had pleural effusion. Forty-seven children (43.9%) had Mycoplasma pneumoniae infection, 28 children (26.2%) had adenovirus infection, and 17 children (15.9%) had influenza virus infection. Seventy-one children (66.4%) had a single occurrence of PB, and 36 cases (33.6%) had recurrent occurrence of PB (≥2 times). Multivariate logistic regression analysis showed that involvement of ≥2 lung lobes (OR=3.376) under bronchoscopy, continued need for invasive ventilation after initial removal of plastic casts (OR=3.275), and concomitant multi-organ dysfunction outside the lungs (OR=2.906) were independent risk factors for recurrent occurrence of PB (P<0.05).
CONCLUSIONS:Children with pneumonia accompanied by persistent high fever, shortness of breath, respiratory failure, atelectasis or pleural effusion should be highly suspected with PB. Involvement of ≥2 lung lobes under bronchoscopy, continued need for invasive ventilation after initial removal of plastic casts, and concomitant multi-organ dysfunction outside the lungs may be risk factors for recurrent occurrence of PB.
