Lignans from stems and leaves of Cephalotaxus fortunei (Ⅱ).
10.19540/j.cnki.cjcmm.20220928.201
- Author:
Jia-Mei TIAN
1
;
Yi-Zhen YUAN
1
;
Jing-Li WANG
1
;
Da-Hong LI
1
;
Jiao BAI
1
;
Hui-Ming HUA
1
Author Information
1. Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, School of Chinese Materia Medica, Shenyang Pharmaceutical University Shenyang 117004, China.
- Publication Type:Journal Article
- Keywords:
Cephalotaxus fortunei;
cephalignan A;
lignans
- MeSH:
Cephalotaxus;
Lignans/analysis*;
Plant Leaves/chemistry*;
Ethanol;
Chromatography, High Pressure Liquid
- From:
China Journal of Chinese Materia Medica
2023;48(7):1892-1898
- CountryChina
- Language:Chinese
-
Abstract:
The present study aimed to explore the chemical constituents from the stems and leaves of Cephalotaxus fortunei. Seven lignans were isolated from the 75% ethanol extract of C. fortunei by various chromatographic methods, including silica gel, ODS column chromatography, and HPLC. The structures of the isolated compounds were elucidated according to physicochemical properties and spectral data. Compound 1 is a new lignan named cephalignan A. The known compounds were identified as 8-hydroxy-conidendrine(2), isolariciresinol(3), leptolepisol D(4), diarctigenin(5), dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucopyranoside(6), and dihydrodehydrodiconiferyl alcohol 4-O-β-D-glucopyranoside(7). Compounds 2 and 5 were isolated from the Cephalotaxus plant for the first time.
