A Rapid and Accurate CRISPR/Cas12b-Mediated Genotyping Assay for the Methylenetetrahydrofolate Reductase Gene Polymorphism C677T.

Author: Xin Xin SI ¹ ; Quan ZHANG ¹ ; Zhi Dan LUO ¹ ; Zhen Yu ZHANG ¹ ; Yan WANG ² ; Li Pei SHAO ³
Author Information

1. Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Co-Innovation Center of Jiangsu Marine Bio-industry Technology, School of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, Jiangsu, China.
2. Department of Pathology, The Second People's Hospital of Lianyungang, Lianyungang 222001, Jiangsu, China.
3. Center for Cellular Engineering, Department of Transfusion Medicine and Cellular Engineering, NIH Clinical Center, Bethesda, MD, USA.
Publication Type:Letter
MeSH: Humans; Methylenetetrahydrofolate Reductase (NADPH2)/metabolism*; Genotype; CRISPR-Cas Systems; Polymorphism, Genetic; Genetic Predisposition to Disease; Polymorphism, Single Nucleotide; Gene Frequency
From: Biomedical and Environmental Sciences 2023;36(6):561-565
CountryChina
Language:English