Prevention and alleviation of neurodegenerative diseases： time restricted feeding
10.19428/j.cnki.sjpm.2023.22695
- VernacularTitle:中枢神经系统退行性病变的预防及控制：时间限制性饮食
- Author:
Hongwei LIU
1
;
Yanfei GUO
2
;
Fan WU
1
Author Information
1. School of Public Health, Fudan University, Shanghai 200032, China
2. Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China
- Publication Type:Review
- Keywords:
time restricted feeding;
neurodegenerative disease;
prevention;
biological mechanism;
aging
- From:
Shanghai Journal of Preventive Medicine
2023;35(6):599-603
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid development of aging around the world， the incidence and prevalence of age-related dementia have increased significantly， leading to a huge burden on patients， families and society. So far， there are no drugs that can completely reverse degeneration of the nervous system. The core pathological mechanisms of dementia are not clear， and the occurrence and progression of degenerative diseases in the nervous system appears to be only rely on the prevention through lifestyle interventions. Among lifestyle interventions， a large amount of laboratory evidence and a small amount of epidemiological evidence suggest that time restricted feeding have excellent effects on preventing the occurrence and progression of degenerative diseases in the nervous system. However， due to the lack of evidence in human population， the application of time restricted feeding lacks scientific basis. By synthesizing the existing evidence， this review discussed the pathway network of time restricted feeding that antagonizes the nervous system degradation， suggesting that future studies should focus on population evidence and the combined effects of multiple effect pathways.
