Research progress on drug resistance mechanism of Candida glabrata
10.12206/j.issn.2097-2024.202202050
- VernacularTitle:光滑念珠菌耐药机制的研究进展
- Author:
Yilan XU
1
;
Lan YAN
2
Author Information
1. School of Basic Medicine, Navy Medical University, Shanghai 200433, China.
2. Center for Drug Discovery and Development,;National Demonstration Center for Experimental Military Pharmacy Education, Navy Medical University, Shanghai 200433, China.
- Keywords:
Candida glabrata;
azole;
echinocandin;
polyene;
drug resistance
- From:
Journal of Pharmaceutical Practice
2023;41(7):393-395
- CountryChina
- Language:Chinese
-
Abstract:
With the increasing proportion of Candida glabrata in patients with candidiasis, C. glabrata has become one of the most common pathogenic Candida in clinical practice. There are limited types of antifungal drugs, and the consequent problem of drug resistance is severely increasing, which brings difficulties to clinical treatment. The resistance mechanisms of C. glabrata to azoles, echinocandins and polyenes were reviewed in this paper.