Research progress in pH-responsive antibacterial nanomaterials for inhibiting oral plaque biofilms.
10.3760/cma.j.cn112144-20221024-00555
- VernacularTitle:pH响应型抗菌纳米材料在抑制口腔菌斑生物膜领域的研究进展
- Author:
Shan Lin QU
1
;
Shuo YU
1
;
Xiao Lin MA
1
;
Rui WANG
1
Author Information
1. Department of Preventive Dentistry, Hospital of Stomatology, Jilin University, Changchun 130021, China.
- Publication Type:Journal Article
- From:
Chinese Journal of Stomatology
2023;58(3):292-297
- CountryChina
- Language:Chinese
-
Abstract:
pH-responsive antibacterial nanomaterials are a new type of nanomaterials that can selectively undergo structural changes and trigger drug release according to significant pH differences produced by the body under physiological and pathological conditions. The formation of acidic microenvironment in plaque is the key to the pathogenicity of oral plaque biofilm, which also creates conditions for the oral application of pH-responsive antibacterial nanomaterials. pH-responsive antibacterial nanomaterials can respond to changes in pH of plaque microenvironment and accurately control the release of antibacterial drugs, providing a new direction for improving drug efficacy and targeted antibacterial. The present article reviews the classification, mechanism and application of pH-responsive antibacterial nanomaterials in oral plaque inhibition.
