Advances in animal models of chronic heart failure and its applications in traditional Chinese medicine.
- Author:
Qian ZHANG
1
;
Xiao-Hong WEI
1
;
Jie CHEN
1
;
Xue-Fen WU
1
;
Xiao-Feng XIA
1
;
Yu-Zhuo WU
1
;
Ling-Yan WANG
1
;
Huan XIA
1
;
Gui-Yang XIA
1
;
Sheng LIN
1
;
Hong-Cai SHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: animal models; chronic heart failure; etiology; pathogenesis; risk factors for CHF development; traditional Chinese medicine
- MeSH: Animals; Medicine, Chinese Traditional; Heart Failure; Heart Diseases; Chronic Disease; Models, Animal
- From: China Journal of Chinese Materia Medica 2023;48(3):614-624
- CountryChina
- Language:Chinese
- Abstract: Chronic heart failure(CHF) is a series of clinical syndromes in which various heart diseases progress to their end stage. Its morbidity and mortality are increasing year by year, which seriously threatens people's life and health. The diseases causing CHF are complex and varied, such as coronary heart disease, hypertension, diabetes, cardiomyopathy and so on. It is of great significance to establish animal models of CHF according to different etiologies to explore the pathogenesis of CHF and develop drugs to prevent and treat CHF induced by different diseases. Therefore, based on the classification of the etiology of CHF, this paper summarizes the animal models of CHF widely used in recent 10 years, and the application of these animal models in traditional Chinese medicine(TCM) research, in order to provide ideas and strategies for studying the pathogenesis and treatment of CHF, and provide ideas for TCM modernization research.
