Progress in perioperative management of ABO-incompatible pediatric liver transplantation.
10.3760/cma.j.cn112139-20220507-00206
- VernacularTitle:儿童ABO血型不相容肝移植围手术期处理的研究进展
- Author:
Hao YU
1
;
Wei Li WANG
1
;
Wei ZHANG
1
;
Xue Li BAI
1
;
Ting Bo LIANG
1
Author Information
1. Liver Transplant Center,Department of Hepatic-Biliary-Pancreatic Surgery,the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China.
- Publication Type:Journal Article
- MeSH:
Adult;
Humans;
Child;
Liver Transplantation;
Postoperative Complications;
Splenectomy
- From:
Chinese Journal of Surgery
2023;61(2):173-176
- CountryChina
- Language:Chinese
-
Abstract:
ABO incompatible(ABO-I) liver grafts will affect the prognosis of liver transplantation. With the improvement of perioperative treatment,including plasma exchange,rituximab,splenectomy,etc.,the prognosis of ABO-I liver transplantation has been greatly improved. Because children's immune systems are not fully developed,the perioperative management of ABO-I pediatric liver transplantation is significantly different from that of adults. Reducing the perioperative anti-donor ABO antibody titer is the key to the perioperative management of ABO-I liver transplantation. This article summarizes literatures on the perioperative management of ABO-I pediatric liver transplantation, including the perioperative anti-rejection regimen in pediatric recipients of different ages, splenectomy, postoperative monitoring and postoperative complications, etc.
