Research progress on the relationship between air pollution and gestational diabetes.
10.3760/cma.j.cn112150-20220218-00153
- VernacularTitle:空气污染与妊娠期糖尿病关系的研究进展
- Author:
Xiao Ling ZENG
1
;
Qing CHEN
2
;
Heng YANG
2
;
Jia CAO
2
;
Ni Ya ZHOU
3
Author Information
1. Institute of Toxicology, Facutly of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing 400038, China School of Public Health, China Medical University, Shenyang 110122, China.
2. Institute of Toxicology, Facutly of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing 400038, China.
3. Chongqing Health Center for Women and Children/Department of Clinical Research Center of Science and Education, Women and Children's Hospital of Chongqing Medical University, Chongqing 400021, China.
- Publication Type:Journal Article
- MeSH:
Pregnancy;
Female;
Humans;
Diabetes, Gestational/epidemiology*;
Air Pollution/analysis*;
Air Pollutants/analysis*;
Particulate Matter/analysis*;
Risk Factors;
Maternal Exposure/adverse effects*
- From:
Chinese Journal of Preventive Medicine
2023;57(2):159-165
- CountryChina
- Language:Chinese
-
Abstract:
Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications and has serious implications for the health of mothers and their offspring. In recent years, studies have confirmed that air pollution is one of the main risk factors for diabetes, and there is increasing evidence that air pollution exposure is closely related to the occurrence of gestational diabetes. However, current studies on the association between air pollutant exposure and the incidence of gestational diabetes are inconsistent, and the window period of pollutant exposure is still unclear. Limited mechanistic studies suggest that airborne particulate matter and gaseous pollutants may affect GDM through multiple mechanisms, including inflammation, oxidative stress, disruption of adipokine secretion, and imbalance of intestinal flora. This review summarizes the relationship between air pollutant exposure and the incidence of GDM in recent years, as well as the possible molecular mechanism of the occurrence and development of GDM caused by air pollutants, in order to provide scientific basis for preventing pollutant exposure, reducing the risk of GDM, improving maternal and fetal outcomes and improving the quality of the birth population.
