Research on quality control standard and safety of liquid bandage

VernacularTitle:液体创可贴的质量控制标准与安全性研究
Author: Hang XU ¹ ; Tianyu WANG ² ; Lingna ZHANG ² ; Hongtao SONG ²
Author Information

1. No. 900 Hospital of Joint Logistics Support Force of the PLA/Fuzong Clinical Medical College of Fujian Medical University, Fuzhou 350025, China;School of Pharmacy, Fujian Medical University, Fuzhou 350108, China.
2. No. 900 Hospital of Joint Logistics Support Force of the PLA/Fuzong Clinical Medical College of Fujian Medical University, Fuzhou 350025, China.
Keywords: liquid bandage; quality control; security
From: Journal of Pharmaceutical Practice 2023;41(2):106-112
CountryChina
Language:Chinese
Abstract: Objective To investigate the quality and safety of liquid bandage and establish a reliable quality control method. Methods The quality of liquid bandage was evaluated by appearance, film forming time, viscosity, comfort, waterproof and air permeability. The content was determined by HPLC. The safety of liquid bandage was investigated with skin irritation test and allergy test. Results The self-made liquid bandage was uniform and delicate, with good ductility, fast film formation, good mechanical strength, waterproof and air permeability. The content of active pharmaceutical ingredients in the film met the requirements. It had no obvious irritation to the skin and no allergic reaction. Conclusion The established quality control method was reliable. The liquid bandage had good safety profile.