Research progress of IgG type 4 autoantibodies in IgG4-AID
10.3760/cma.j.cn114452-20220124-00037
- VernacularTitle:IgG4型自身抗体在IgG4-AID中的研究进展
- Author:
Bao ZHAO
1
;
Li YAN
;
Yin XIONG
;
Tianpen CUI
Author Information
1. 湖北中医药大学检验学院2021级医学技术专业，武汉430065
- Keywords:
Immunoglobulin G;
Autoantibodies;
Autoimmune diseases
- From:
Chinese Journal of Laboratory Medicine
2022;45(9):992-996
- CountryChina
- Language:Chinese
-
Abstract:
Immunoglobulin G4 autoimmune diseases (IgG4-AID) is the general name of a series of autoimmune diseases, including membranous nephropathy, pemphigus and myasthenia gravis. It is mainly characterized by the existence of IgG4 autoantibodies in patients. At present, a variety of IgG4-AID-related autoantigens have been found, which mainly exist in kidney, skin, central and peripheral nervous system, blood circulation or vascular system. Compared with IgG autoantibodies, various IgG4 autoantibodies have better clinical significance or clinical-laboratory value in the diagnosis, differential diagnosis, treatment and prognosis judgment of some IgG4-AID. This article reviews the research progress of IgG4 autoantibodies in IgG4-AID.
