Safety risk assessment of fluoride in brick-tea and consideration and suggestions on its limit in China at the present stage
10.3760/cma.j.cn231583-20220318-00082
- VernacularTitle:对现阶段我国砖茶氟的安全风险评估及其限量的思考与建议
- Author:
Lijun ZHAO
1
;
Yanhui GAO
;
Dianjun SUN
Author Information
1. 哈尔滨医科大学中国疾病预防控制中心地方病控制中心 国家卫生健康委病因流行病学重点实验室（23618504）黑龙江省微量元素与人类健康重点实验室，哈尔滨 150081
- Keywords:
Fluorine;
Brick-tea;
Safety risk assessment;
Drinking brick-tea type of endemic fluorosis;
Limit
- From:
Chinese Journal of Endemiology
2022;41(8):603-608
- CountryChina
- Language:Chinese
-
Abstract:
Drinking brick-tea type of endemic fluorosis is a kind of chronic fluorosis caused by excessive intake of fluoride into the body from long-term and high consumption of brick-tea, milk tea, butter tea, or other tea drinks with high fluoride content. It mainly distributes in seven western provinces of China, including Tibet Autonomous Region, Qinghai Province, Sichuan Province, Xinjiang Uygur Autonomous Region, Inner Mongolia Autonomous Region, Gansu Province, and Ningxia Hui Autonomous Region. In order to govern the production and sale of brick-tea and control the epidemic of drinking brick-tea type of endemic fluorosis, the former Ministry of Health of China issued the national standard "Fluoride Content of Brick-tea" (GB 19965-2005) in 2005, which stipulated that the total amount of water-soluble inorganic fluorine in brick-tea should not exceed 300 mg/kg. In the past 20 years, the prevalence of drinking brick-tea type of endemic fluorosis in China became clear gradually, and the habit of drinking brick-tea of residents in the epidemic fluorosis area also changed to some extent. In this paper, the dose-effect relationship between fluoride intake from brick-tea and skeletal fluorosis is reviewed, the brick-tea consumption of residents in the endemic fluorosis areas is analyzed, and the safety risk of brick-tea fluoride exposure is evaluated. It is suggested that the fluoride limit of brick-tea, ≤300 mg/kg, is still suitable for the prevention and control of drinking brick-tea type of endemic fluorosis in China at the present stage.
