Fetal inflammatory response syndrome and neonatal clinical outcomes
10.3760/cma.j.issn.1673-4912.2022.10.013
- VernacularTitle:胎儿炎症反应综合征与新生儿临床结局
- Author:
Ying SHAN
1
;
Jianhua FU
Author Information
1. 中国医科大学附属盛京医院儿内科，沈阳 110004
- Keywords:
Fetal inflammatory response syndrome;
Diagnosis;
Clinical outcomes;
Newborn
- From:
Chinese Pediatric Emergency Medicine
2022;29(10):823-827
- CountryChina
- Language:Chinese
-
Abstract:
Fetal inflammatory response syndrome(FIRS) is a state of systemic inflammatory response in the fetus, induced by infectious and non-infectious pathways, with increased levels of cytokines represented by interleukin-6.Chorioamnionitis and funisitis are common placental pathological changes of FIRS.FIRS can not only lead to premature birth, but also is closely related to multiple organ damage such as brain injury, lung injury, early-onset sepsis, necrotizing enterocolitis, and cardiovascular system diseases during the neonatal period.Therefore, reducing the damage caused by FIRS to neonates is a common clinical problem that obstetricians and pediatricians will face together.
