Advances in the application of exosomes of mesenchymal stem cells carrying miRNA-126 in septic shock cardiac dysfunction
10.3760/cma.j.issn.1673-4912.2022.10.012
- VernacularTitle:负载miRNA-126的间充质干细胞外泌体在脓毒性休克心功能障碍机制中的研究进展
- Author:
Li WANG
1
;
Chunfeng LIU
Author Information
1. 中国医科大学附属盛京医院儿科，沈阳 110004
- Keywords:
Sepsis;
Cardiac dysfunction;
Exosome;
miRNA-126
- From:
Chinese Pediatric Emergency Medicine
2022;29(10):817-822
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes play important roles in cell communication and information transmission.miRNA-126 carried by mesenchymal stem cells exosomes can reduce inflammatory response and protect vascular endothelium by regulating protein expression, thus blocking or alleviating cardiac dysfunction during septic shock, which is expected to become a new way to treat septic shock cardiac dysfunction.
