Research progresses on the cognitive impairment of Duchenne muscular dystrophy

VernacularTitle:Duchenne型肌营养不良患儿认知损害的研究进展
Author: Xiaofang ZHANG ¹ ; Siqi HONG
Author Information

1. 重庆医科大学附属儿童医院神经内科，儿童发育疾病研究教育部重点实验室，国家儿童健康与疾病临床医学研究中心，儿童发育重大疾病国家国际科技合作基地，儿科学重庆市重点实验室，重庆　400014
Keywords: Duchenne muscular dystrophy; Dystrophin gene; Cognitive impairment
From: Chinese Journal of Applied Clinical Pediatrics 2022;37(12):954-957
CountryChina
Language:Chinese
Abstract: Duchenne muscular dystrophy(DMD) is an X-linked hereditary neuromuscular disorder caused by dystrophin gene mutation.About 1/3 of DMD patients have cognitive impairment.Early detection of cognitive impairment is essential for early diagnosis and the quality of life.This review summarized the recent progress in the clinical features, pathogenesis, brain structure changes, and cognitive impairment intervention of DMD.