Locus Coeruleus Acid-Sensing Ion Channels Modulate Sleep–Wakefulness and State Transition from NREM to REM Sleep in the Rat
10.1007/s12264-020-00625-0
- Author:
Fayaz A. MIR
1
;
Sushil K. JHA
1
Author Information
1. School of Life Sciences, Jawaharlal Nehru University
- Publication Type:Journal Article
- Keywords:
Acid-sensing ion channels;
Carbon dioxide;
Hypercapnia;
NREM sleep;
REM sleep
- From:
Neuroscience Bulletin
2021;37(5):684-700
- CountryChina
- Language:Chinese
-
Abstract:
The locus coeruleus (LC) is one of the essential chemoregulatory and sleep–wake (S–W) modulating centers in the brain. LC neurons remain highly active during wakefulness, and some implicitly become silent during rapid eye movement (REM) sleep. LC neurons are also involved in CO
