Antimicrobial activity of some essential oils against oral multidrug-resistant Enterococcus faecalis in both planktonic and biofilm state
10.12980/APJTB.4.2014C1203
- Author:
Fethi BENBELAÏD
1
;
Abdelmounaïm KHADIR
1
;
Mohamed Amine ABDOUNE
1
;
Mourad BENDAHOU
1
;
Alain MUSELLI
2
;
Jean COSTA
2
Author Information
1. Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Aboubekr Belkaïd University
2. Laboratory of Natural Products Chemistry, University of Corsica, UMR CNRS 6134
- Publication Type:Journal Article
- Keywords:
Bacterial infections;
Biofilm;
Enterococcus faecalis;
Essential oils;
Multidrug-resistance
- From:Asian Pacific Journal of Tropical Biomedicine
2014;4(6):463-472
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate some essential oils in treatment of intractable oral infections, principally caused by biofilm of multidrug-resistant Enterococcus faecalis (E. faecalis), such as persistent endodontic infections in which their treatment exhibits a real challenge for dentists. Methods: Ten chemically analyzed essential oils by gas chromatography-mass spectrometry were evaluated for antimicrobial activity against sensitive and resistant clinical strains of E. faecalis in both planktonic and biofilm state using two methods, disk diffusion and broth micro-dilution. Results: Studied essential oils showed a good antimicrobial activity and high ability in E. faecalis biofilm eradication, whether for sensitive or multidrug-resistant strains, especially those of Origanum glandulosum and Thymbra capitata with interesting minimum inhibitory concentration, biofilm inhibitory concentration, and biofilm eradication concentration values which doesn't exceed 0.063%, 0.75%, and 1.5%, respectively. Conclusions: Findings of this study indicate that essential oils extracted from aromatic plants can be used in treatment of intractable oral infections, especially caused by biofilm of multidrug-resistant E. faecalis.
