Microarray analysis of PBMC after Plasmodium falciparum infection: Molecular insights into disease pathogenesis
10.1016/j.apjtm.2016.03.013
- Author:
Wan-Chung HU
1
Author Information
1. Department of International Health, Johns Hopkins University School of Public Health, Division of Clinical Chinese Medicine, National Research Institute of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Anemia;
Cerebral malaria;
Coagulopathy;
Fever;
Hypoglycemia;
Metabolic acidosis
- From:
Asian Pacific Journal of Tropical Medicine
2016;9(4):313-323
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To find out host gene expression profiles after malarial infection. Methods: Further time-course microarray analysis of peripheral blood mononuclear cells focusing on malaria pathogenesis was performed. Results: Up-regulation of coagulation-related genes, heat shock proteins, glycolytic enzymes, glucose transporters, and vacuolar H
