Ethnobotanical database based screening and identification of potential plant species with antiplasmodial activity against chloroquine-sensitive (3D7) strain of Plasmodium falciparum

Author: Monica NORONHA ¹ ; Monica SUBRAMANIAN ¹ ; Shivali GULERIA ² ; Dhara JANI ² ; Dhara GEORGE ² ; Hyacinth HIGHLAND ²
Author Information

1. P. G. Department of Biosciences, Centre of Advanced Studies, Satellite Campus, Sardar Patel University
2. Department of Zoology, Biomedical Technology and Human Genetics, School of Sciences, Gujarat University
Publication Type:Journal Article
Keywords: Antioxidant; Antiplasmodial; Ethnobotany; Plasmodium falciparum
From:Asian Pacific Journal of Tropical Biomedicine 2018;8(2):92-97
CountryChina
Language:Chinese
Abstract: Objective: To evaluate the antiplasmodial activity of aqueous-methanolic plant extracts of nine plant species selected, based on ethnobotanical data. Methods: Based on ethnobotanical database, the selected plants were tested for their antiplasmodial activity against chloroquine-sensitive (3D7) strain of Plasmodium falciparum. Qualitative tests and high performance thin layer chromatography analysis were carried out to explore the phytocomponents present in the plant extracts. 1,1-diphenyl-2-picrylhydrazyl antioxidant activity was also determined to check the antioxidant activity of the plant extracts. Results: Moringa oleifera (IC