Surface Characteristics and Biocompatibility of Micro Arc Oxidized Titanium Alloy.
- Author:
Young Wook LIM
1
;
Eun Sang LEE
;
Yong Sik KIM
;
Kwang Yun SONG
;
Soon Yong KWON
Author Information
1. Department of Orthopedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. sykwon@catholic.ac.kr
- Publication Type:In Vitro ; Original Article
- Keywords:
Micro Arc Oxidized (MAO);
Biocompatibility;
Titanium Alloy
- MeSH:
Alloys*;
Cell Differentiation;
Cell Line;
Collagen;
Cytoskeleton;
Gene Expression;
Osteoblasts;
Osteocalcin;
Plasma;
Titanium*
- From:Journal of Korean Orthopaedic Research Society
2015;18(1):9-17
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this research was to characterize micro arc oxidized titanium (MAO-Ti), accompanied by biocompatibility test in vivo as well as in vitro in comparison to the different types of surface modification; machined, blasted and plasma spray. MATERIALS AND METHODS: XRD and SEM investigations were performed in order to assess the structure and morphology. Biologic and morphologic responses to the osteoblast cell lines (Saos-2) were then examined, using Promeg(R) proliferation assay, alkalinephosphatase activity, alphavbeta3 integrin expression and cytoskeleton staining (Rhodamine-Phallodine). The analysis of gene expression for osteocalcin and collagen I was done through RT-PCR. RESULTS: MAO-Ti showed more activity on osteointegration and cell differentiation compared to other types of surface modification. CONCLUSION: In summary, MAO-Ti appears to exhibit more favorable biocompatibility than the compared groups in vitro and in vivo as well.
