Location， Pattern and Prognosis of Tumor Metastasis in Dead Patients with Colorectal Cancer
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2022.0215
- VernacularTitle:结直肠癌死亡患者的肿瘤转移部位、发生率及预后
- Author:
Jia-ming ZHOU
1
;
Xiao-feng WU
2
;
Yuan-hui WU
1
;
Xiao-qiong CHEN
1
;
Shu-yun TAN
1
;
Tuo-yang LI
1
;
Xue-bin SHI
1
;
Mei-jin HUANG
1
Author Information
1. Department of Colon and Rectum Surgery， Sixth Affiliated Hospital of Sun Yat-sen University， Guangzhou 510655， China
2. Department of Medical Records Management， Sixth Affiliated Hospital of Sun Yat-sen University， Guangzhou 510655， China
- Publication Type:Journal Article
- Keywords:
colorectal cancer;
metastasis;
death
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2022;43(2):289-296
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveIn the past， many studies have reported the mode of colorectal cancer（CRC） metastasis， but there is still a lack of research based on long-term follow-up and death as the end point to summarize the location， mode and related survival data of CRC metastasis. MethodsThe data of 373 dead patients with colorectal cancer in the Sixth Affiliated Hospital of Sun Yat-sen University were reviewed， and the location， mode， incidence and survival data of tumor metastasis were statistically analyzed. Results334 patients （89.5%） died of tumor related death. The liver metastasis rate was 51.5%， the lung metastasis rate was 40.4%， and the peritoneal metastasis rate was 55.7%. The number of patients with liver， lung or peritoneal metastasis only was 27 （8%）， 21 （6.3%） and 63 （18.9%） respectively. The prognosis of patients with simple lung metastasis was better （P<0.01）. There were 66 patients （19.7%） with simultaneous metastasis of liver， lung and peritoneum， and the prognosis was the worst （P<0.01）. ConclusionNot all dead colorectal cancer patients have simultaneous metastasis of liver， lung and peritoneum. There are differences in the location and mode of metastasis in different patients， which is related to survival.
