Clinical Charateristics and Prognosis of Takotsubo Syndrome Mimicking Acute Myocardial Infarction
- VernacularTitle:酷似急性心肌梗死的Takotsubo 综合征临床特点及预后分析
- Author:
Jun LIU
1
;
Jun LAI
1
;
Yong-cong HE
1
;
Xiao-xue ZHANG
1
Author Information
1. The 2nd Department of Cardiology, Guangdong No.2 Provincial People’s Hospital, Guangzhou 510317, China
- Publication Type:Journal Article
- Keywords:
Takotsubo syndrome;
stress cardiomyopathy;
acute myocardial infarction;
clinical characteristics
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2020;41(4):627-634
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the clinical characteristics, imaging characteristics and prognosis of Takotsubo syndrome(TTS), so as to avoid missing diagnosis and mistreatment, and to take corrective measures in time. 【Methods】 Retrospective analysis of the data and outcome of 10 cases of TTS mimicking acute myocardial infarction. 【Results】 The ECG of 10 patients with TTS showed ST-segment elevation and large territory changes in the later stage. Male to female ratio was 1/9. The patients’age range was 49~83(69.70±9.83) years. Laboratory tests of CTnI increased moderately, but NT-proBNP increased significantly, accompanied by left ventricular dysfunction; all 10 cases of coronary angiography did not show obvious coronary lesions, but slow-flow occurred in 4 cases, of which 9 patients had left ventricular angiography to confirm TTS. One patient underwent IABP due to hypotension, the rest were treated conservatively with medication. One patient had lung cancer recurrence, worsening heart failure, and died 4 days after onset. Nine patients improved and were discharged from the hospital and the left ventricular function of their cardiac color Doppler ultrasound finding was significantly improved. In the 2 to 24 months follow-up, 9 discharged patients all survived without recurrence. 【Conclusions】 The clinical manifestations of TTS are very similar to those of myocardial infarction, and it can be easily misdiagnosed or missed. Generally, it has good prognosis. However, the increased NT-proBNP index after treatment may indicate a poor prognosis.
