Efficacy of magnetic resonance IDEAL-IQ technique in diagnosis of fat and iron deposition in acute pancreatitis
10.3969/j.issn.1001-5256.2022.10.022
- VernacularTitle:磁共振IDEAL-IQ技术对急性胰腺炎患者脂肪与铁沉积的诊断效能分析
- Author:
Huifang FAN
1
;
Qiang CHEN
2
;
Xiaojun YUAN
2
;
Lin LUO
2
Author Information
1. Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region 014040, China
2. Department of Medical Radiology, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region 014010, China
- Publication Type:Original Article_Pancreatic Diseases
- Keywords:
Pancreatitis;
IDEAL-IQ;
Fat Deposition;
Iron Deposition
- From:
Journal of Clinical Hepatology
2022;38(10):2320-2324
- CountryChina
- Language:Chinese
-
Abstract:
Objective To perform quantitative evaluation of fat and iron deposition in the pancreas of patients with acute pancreatitis (AP) based on the IDEAL-IQ quantitative parameters fat fraction (FF) and relaxation rate (R 2 * ), and to investigate the efficacy of this technique in the diagnosis of AP. Methods A total of 72 patients with AP who were diagnosed and treated in The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology from October 2020 to October 2021, were enrolled as case group, and 82 healthy controls who underwent physical examination during the same period of time were enrolled as control group. The abdominal IDEAL-IQ sequence test was performed for both groups using GE 3.0T magnetic resonance instrument, and FF and R 2 * values were measured on post-processing workstation. The t -test was used for comparison of normally distributed continuous data between groups, and the Mann-Whitney U test was used for comparison of non-normally distributed continuous data between groups. A receiver operating characteristic (ROC) curve analysis was performed for the parameters with statistical significance, and area under the ROC curve ( AUC ) was used to evaluate the diagnostic efficacy of parameters. Results Compared with the control group, the case group had significantly higher FF value ( Z =-10.01, P < 0.001) and R 2 * value ( Z =-3.73, P < 0.001), while there were no significant differences in FF and R 2 * values between mild AP and moderate-to-severe AP ( P > 0.05). FF value had a sensitivity of 100% and a specificity of 90.2% in the diagnosis of AP, while R 2 * value had a sensitivity of 48.6% and a specificity of 86.6% in the diagnosis of AP. Conclusion The quantitative parameter FF value of magnetic resonance IDEAL-IQ technique has relatively high sensitivity and specificity in the diagnosis of AP, and it is a specific index for the diagnosis of AP and holds promise for clinical application.
