Location of Bile Leakage may be a Relevant Factor Influencing the Success of the First ERCP
- VernacularTitle:胆漏的位置可能是影响首次内镜逆行胰胆管造影术成功的相关因素
- Author:
Zhang-jun WEI
1
;
Liang-qi CAO
2
;
Shi-rong CHEN
2
Author Information
1. Department of General Surgery， People's Hospital of Shapingba District， Chongqing 400030， China
2. Department of Hepatobiliary Surgery， The Second Affiliated Hospital of Guangzhou Medical University， Guangzhou 510260， China
- Publication Type:Journal Article
- Keywords:
endoscopic;
biliary leak;
stent
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2021;42(1):154-160
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the location of bile leakage as a relevant factor influencing the success of the first endoscopic retrograde cholangiopancreatography （ERCP） procedure. MethodsA retrospective analysis was conducted to investigate clinical data coming from the Second Affiliated Hospital of Guangzhou Medical University from June 2012 to April 2017. Data were collected from patients with suspected biliary leakage HBP post-operation. All of the patients having undergone ERCP procedure were divided into the cystic duct leakage group （9 cases） and the intrahepatic bile duct leakage group （10 cases）. A statistical analysis was performed on WBC counts， liver function changes， and improvement of the disease. ResultsAll of the 19 cases had successfully completed the ERCP treatment with no serious postoperative complications. Especially， GI bleeding， perforation， infection and shock were not found. Unfortunately， no significant differences were observed in WBC counts， liver function changes and improvement between the two groups before and after the operation （P>0.05）. Interestingly， the first successful ERCP procedure was assigned as Group A （n=11）， the first unsuccessful ERCP procedure was assigned as Group B （n=8）. A univariate analysis on the influence of gender， age， preoperative ALT， AST， TBIL and surgery type on the success of the first ERCP procedure had shown no statistical difference （P=0.650， P=0.869， P=0.481， P=0.620， P=0.340， P=0.362）， while there were statistical differences in WBC count （P=0.015） and bile leakage location （P=0.020）. An exact Logistic regression analysis had shown that there was a significant difference in the location of bile leakage （P=0.0004， OR=5.448， 95%CI=2.347~+∞）. ConclusionsBile leakage treated with ERCP method is safe and effective. The location of bile leakage is a relevant factor influencing the success of the first ERCP procedure.
