Current status of the research on microenvironment-targeting therapy and immunotherapy for liver cancer
10.3969/j.issn.1001-5256.2022.08.038
- VernacularTitle:肝癌微环境靶向与免疫治疗的研究现状
- Author:
Mingqiang ZHU
1
;
Youming DING
1
Author Information
1. Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China
- Publication Type:Reviews
- Keywords:
Liver Neoplasms;
Tumor Microenvironment;
Therapeutics
- From:
Journal of Clinical Hepatology
2022;38(8):1913-1917
- CountryChina
- Language:Chinese
-
Abstract:
Tumor microenvironment is composed of tumor cells and their internal and external environment, and the components vary slightly between different types of tumor. Liver cancer microenvironment is a tumor-promoting microenvironment constructed by hepatoma cells and immune cells and can lead to the development, invasion, and metastasis of liver cancer by recruiting inflammatory cells, inhibiting antitumor immune response, promoting angiogenesis, and promoting drug resistance. This article discusses the characteristics of liver cancer microenvironment, the composition and role of liver cancer microenvironment, and the new advances in microenvironment-targeting therapy for liver cancer.
