Research update on the effect of adverse childhood experience on telomere morphology

VernacularTitle:童年期不良经历对端粒形态影响的研究进展
Author: XIAO Wan, WAN Yuhui ¹
Author Information

1. Department of Maternal, Child & Adolescent Health, School of Public Health/MOE Key Laboratory of Population Health across Life Cycle/Anhui Provincial Key Laboratory of Population Health & Aristogenics, Anhui Medical University, Hefei (230032) , China
Publication Type:期刊文章
Keywords: Life change events; Telomere; Child; Adolescent; Life cycle stages; Mental health
From: Chinese Journal of School Health 2022;43(8):1272-1275
CountryChina
Language:Chinese
Abstract: Abstract:Adverse childhood experiences (ACEs) not only affect individual s physical and mental health but also have adverse intergenerational effects. A growing body of researches focused on biological mechanism of ACEs, among which the emerging role of telomere has gained much attention. This article reviews the association between ACEs and telomere morphology during different developmental stages and the role of telomere in adverse health effects of ACEs. It aims to summarize possible mechanisms underlying negative effects of ACEs.