The putative NAD(P)H Nitroreductase, Rv3131, is the Probable Activating Enzyme for Metronidazole in <i>Mycobacterium Tuberculosis</i>.

Author: Wen Zhu DONG ¹ ; Jin SHI ² ; Ping CHU ³ ; Rong Mei LIU ² ; Shu An WEN ⁴ ; Ting Ting ZHANG ⁴ ; Yu PANG ⁴ ; Jie LU ³
Author Information

1. Department of Infectious Diseases, The First People's Hospital of Ziyang, Ziyang 641300, Sichuan, China;Department of Bacteriology and Immunology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing 101149, China.
2. Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
3. Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, MOE Key Laboratory of Major Diseases in Children, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 101149, China.
4. Department of Bacteriology and Immunology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing 101149, China.
Publication Type:Letter
MeSH: Bacterial Proteins; Humans; Metronidazole/pharmacology*; Mycobacterium tuberculosis; NAD; Nitroreductases; Tuberculosis, Lymph Node
From: Biomedical and Environmental Sciences 2022;35(7):652-656
CountryChina
Language:English