The function of auditory cortex in the elderly using functional near-infrared spectroscopy technology.
10.3760/cma.j.cn115330-20210818-00558
- VernacularTitle:基于功能性近红外光谱成像技术研究增龄对听觉皮层言语感知功能的影响
- Author:
Liu YANG
1
;
You Nuo CHEN
1
;
Song Jian WANG
1
;
Yuan WANG
1
;
Ting CHEN
2
;
Ying LIANG
2
;
Shuo WANG
1
Author Information
1. Department of Otolaryngology Head and Neck Surgery, Beijing Institute of Otolaryngology, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Beijing 100730, China.
2. School of Biomedical Engineering, Capital Medical University, Beijing 100069, China.
- Publication Type:Journal Article
- MeSH:
Acoustic Stimulation/methods*;
Adolescent;
Adult;
Aged;
Auditory Cortex/physiology*;
Female;
Humans;
Male;
Middle Aged;
Spectroscopy, Near-Infrared;
Speech Perception/physiology*;
Technology;
Young Adult
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2022;57(4):458-466
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Functional near-infrared spectroscopy (fNIRS) was used to study the effect of aging on the neuroimaging characteristics of cerebral cortex in the process of speech perception. Method: Thirty-four adults with normal hearing were recruited from March 2021 to June 2021, including 17 in the young group, with 6 males, 11 females, age (32.1±5.0) years, age range 20-39 years. and 17 in the elderly group, with 6 males, 11 females, age (63.2±2.8) years, age range 60-70 years. The test material was the sentence table of the Mandarin Hearing Test in Noise (MHINT). The task state block experiment design was adopted, and the temporal lobe, Broca's area, Wernicke's area, motor cortex were used as regions of interest. Objective brain imaging technology (fNIRS) combined with subjective psychophysical testing method was used to analyze the activation area and degree of cerebral cortex related to auditory speech perception in the elderly and young people under different listening conditions (quiet, signal-to-noise ratio of 10 dB, 5 dB, 0 dB, -5 dB). SPSS 23 software was used for statistical analysis. Result: The activation area and degree of activation in the elderly group were lower than those in the young group under each task condition; The number of activation channels in the young group were significantly more than those in the old group, and the number of activation channels in the left hemisphere were more than those in the right hemisphere, but there was no difference in the number of activation channels. There were more channels affected by age in the left hemisphere than in the right hemisphere. The activation degree of the young group when the signal-to-noise ratio was 0 dB was significantly higher than that of other signal-to-noise ratio conditions (P<0.05), but there was no significant difference in the old group under the five conditions (P>0.05). The speech recognition score of the young group was higher than that of the old group under all conditions. When the quiet and signal-to-noise ratio was 10 dB, the correct score of the two groups was equal or close to 100%. With the gradual decrease of signal-to-noise ratio, there was a significant difference between the two groups when the signal-to-noise ratio was 5 dB. The speech recognition accuracy of the young group decreased significantly when the signal-to-noise ratio was 0 dB, while that of the old group decreased significantly when the signal-to-noise ratio was 5 dB. Conclusions: With the increase of age, the speech perception in noisy environment and the activity of cerebral cortex gradually deteriorate, and the speech dominance hemisphere (left hemisphere) will be significantly affected by aging. The overall activation area and activation degree of the elderly under different speech tasks are lower than those of the young.
