Predictive value of impedance of leadless pacemaker during implantation on trend changes of pacing threshold.
10.3760/cma.j.cn112148-20211130-01034
- VernacularTitle:无导线起搏器置入术中阻抗对起搏阈值变化趋势预测价值初探
- Author:
Zhen Jiang LIU
1
;
Zhi Hong WU
1
;
Yi Chao XIAO
1
;
Ying Xu MA
1
;
Xu Ping LI
1
;
Hui YANG
1
;
Tao TU
1
;
Sheng Hua ZHOU
1
;
Qi Ming LIU
1
Author Information
1. Department of Cardiology, Second Xiangya Hospital of Central South University, Changsha 410011, China.
- Publication Type:Journal Article
- MeSH:
Aged;
Aged, 80 and over;
Cardiac Pacing, Artificial;
Cross-Sectional Studies;
Electric Impedance;
Humans;
Male;
Middle Aged;
Pacemaker, Artificial;
Retrospective Studies;
Treatment Outcome
- From:
Chinese Journal of Cardiology
2022;50(2):150-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the predictive value of the impedance measured during leadless pacemaker Micra implantation on the trend of changes of pacing threshold post implantation. Methods: This is a retrospective cross-sectional study. Patients who received implantation of leadless pacemaker Micra at the Second Xiangya Hospital of Central South University from December 2019 to August 2020 were enrolled. The clinical data and the intraoperative electrical parameters during leadless pacemaker implantation were collected. The impedance and pacing threshold data were analyzed at three time points: immediate release, 5-10 min after release, and after traction test. Receiver operating characteristic (ROC) curves and the area under the curve (AUC) were used to analyze the value of the impedance at immediate release on predicting the trend of changes of pacing threshold post implantation. Results: A total of 21 patients (mean age: (72.2±12.5) years, 12 males) were included. The impedance of 21 patients was (798.1±35.3) Ω immediately after implantation, (800.9±35.6) Ω after 5-10 minutes of release, and (883.6±31.7) Ω after traction test. Impedance was similar between the three time points (P>0.05). The threshold was (0.97±0.11) V/0.24 ms immediately after implantation, (0.95±0.12) V/0.24 ms at 5-10 min after the release, and (0.59±0.06) V/0.24 ms after the traction test. The threshold was significantly lower after the traction test than that immediately after release (P=0.003) and than that at 5-10 minutes after release (P=0.008), suggesting a decreased tendency of the threshold over time. According to the analysis of the ROC curve, the immediate impedance after the release ≥680 Ω could predict the ideal pacing threshold after the traction test (AUC=0.989, 95%CI 0.702-0.964, P<0.001), the prediction sensitivity was 87%, and the specificity was 100%. The pacing threshold would be not ideal with the immediate impedance ≤ 520 Ω (95%CI 0.893-1.000, P<0.001), the sensitivity was 100%, and the specificity was 80%. Conclusions: The impedance immediately after the release has predictive value for the changing trend of threshold post leadless pacemaker Micra implantation. Impedance ≥680 Ω immediately after release is often related with ideal pacing threshold after the traction test. In contrast, the impedance ≤ 520 Ω pacing is often related with unsatisfactory threshold after the traction test, therefore, it is recommended to find a new pacing site to achieve the impedance ≥680 Ω immediately after release during leadless pacemaker Micra implantation.
