Pay attention to the role of anti-inflammatory in the treatment of diabetic retinopathy
10.3760/cma.j.cn431274-20211217-01332
- VernacularTitle:重视抗炎在糖尿病视网膜病变治疗中的作用
- Author:
Tiantian CHENG
1
;
Youxin CHEN
Author Information
1. 北京协和医院眼科，中国医学科学院北京协和医学院，北京 100730
- Keywords:
Diabetic retinopathy;
Anti-inflammatory treatment;
Inflammatory reaction;
Glucocorticoid;
Non-steroidal anti-inflammatory drugs
- From:
Journal of Chinese Physician
2022;24(1):1-8
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic retinopathy (DR) is a retinal microvascular disease associated with diabetes which is the primary cause of impaired vision in working age population. Inflammatory reaction and inflammatory factors such as tumor necrosis factor-α (TNF-α) and interleukin (IL)-1β play an important role in the occurrence and development of DR, and to target at which anti-inflammatory treatments such as glucocorticoids and non-steroidal anti-inflammatory drugs were used, but with disputes on therapeutic effect and drug selection. This review aims to clarify the research on mechanism of inflammatory reaction in DR, summarize the application status of existing anti-inflammatory therapy, and provide some new ideas for the research and clinical application of the treatment of DR.
