Research progress of tumor stroma ingredient and pathological features in gastric cancer
10.3760/cma.j.cn115610-20220216-00090
- VernacularTitle:肿瘤间质成分及病理学特征在胃肿瘤中的研究进展
- Author:
Yan YANG
1
;
Tengfei LI
;
Chen HUANG
Author Information
1. 上海交通大学附属第一人民医院胃肠外科，上海 200080
- Keywords:
Stomach neoplasms;
Tumor stroma;
Immune microenvironment;
Patho-logy;
Progress;
Review
- From:
Chinese Journal of Digestive Surgery
2022;21(3):427-432
- CountryChina
- Language:Chinese
-
Abstract:
The main components of the gastric tumor stroma consist of cells in both the immune and non-immune microenvironments. The effectiveness of a series of therapeutic measures such as adjuvant chemotherapy is closely related to the composition of gastric tumor stroma. By analyzing the components in the gastric tumor stroma, we understand the characteristics of the constituents in the pathological structure of gastric cancer, and further explore the connection of each component of the stroma with pathological structure and regulatory mechanisms of stroma components on the occurrence and progression of gastric tumors. Combined with artificial intel-ligence technology to analyze the pathological features related to stroma components of tumor microenvironment, the dynamic changes of immune microenvironment and non-immune microen-vironment in gastric cancer are expected to reveal.
