Research progress on risk factors of spontaneous intestinal perforation in premature infants
10.3760/cma.j.issn.1673-4912.2022.01.015
- VernacularTitle:早产儿自发性肠穿孔危险因素的研究进展
- Author:
Wenwen HE
1
;
Mingyan HEI
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院新生儿中心 100045
- Keywords:
Spontaneous intestinal perforation;
Premature infants;
Risk factors
- From:
Chinese Pediatric Emergency Medicine
2022;29(1):75-77
- CountryChina
- Language:Chinese
-
Abstract:
Spontaneous intestinal perforation(SIP) is one of the causes of digestive tract perforation in premature infants and requires surgical intervention.Except for preterm delivery, the etiology and pathogenesis of SIP remain unclear.The studies have shown that it may be related to the application of magnesium sulfate, nonsteroidal anti-inflammatory drugs, hormones, vasoactive drugs and low perfusion status, infection, congenital intestinal dysplasia, non-invasive respiratory support, delayed nutrition initiation and other factors.In the management of premature infants, it is particularly important to improve the understanding of SIP, early diagnosis and treatment.