Comparative analysisof Saponins in different medicinal parts of Panax Ginseng
10.3760/cma.j.cn115398-20210406-00050
- VernacularTitle:人参不同药用部位皂苷类成分差异性分析
- Author:
Jian GU
1
;
Dongmei WANG
;
Weijuan XU
;
Minhui GAO
Author Information
1. 江苏联合职业技术学院南通卫生分院药学系，南通 226007
- Keywords:
Panax ginseng;
Medicinal parts;
Saponins;
Difference
- From:
International Journal of Traditional Chinese Medicine
2022;44(5):551-554
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the differences of Saponins in different parts of Panax ginseng, which couldprovide reference for a comprehensive quality evaluation.Methods:UFLC- Triple-TOF-MS/MS was used to analyze the Saponins in Ginseng Radix et Rhizoma, Ginseng Folium and Ginseng Flos,The analysis was carried out on a SynergiTM Hydro-RP 100A column, Gradient elution of water (containing 0.1% formic acid) (A)-acetonitrile (B). Principal component analysis (PCA) was used to analyze the grouping of samples, and partial least squares regression (PLS-DA) was used to classify the samples to find the differences of chemical components in different medicinal parts of Panax ginseng. Significant differences in saponins and its rules were found by multivariate statistical analysis.Results:PCA indicated that there was remarkable difference in saponins of Ginseng Radix et Rhizoma, Ginseng Folium and Ginseng Flos, ten different components were found by PLS-DA. Conclusion:There exists obvious differences of different medicinal parts of Panax Ginseng which could provide foundation for the further research and rathional use of Panax ginseng.
