Effects of inflammation and immunoregulatory responses in the formation of peritoneal adhesion

VernacularTitle:炎症与免疫调节反应在腹腔粘连形成中的作用
Author: Lijie JIANG ¹ ; Jing CHEN ; Zhiwen YAN ; Ze CHEN ; Zhiwei YUE ; Hong SUN
Author Information

1. 华北理工大学基础医学院，河北省慢性疾病重点实验室，唐山　063000
Keywords: Peritoneal adhesion; Inflammation reaction; Immune regulation
From: International Journal of Biomedical Engineering 2021;44(5):401-405,417
CountryChina
Language:Chinese
Abstract: Peritoneal adhesion (PA) is a high morbidity complication after surgical procedures, with serious clinical consequences and requiring substantial medical expenditure. The pathogenesis of PA is complex and is still not very clear. Clinically, it is mainly treated by optimizing surgical protocols, using anti-adhesion drugs and biomaterial barriers. Although these methods have shown certain preventive effects, the effectiveness needs to be further improved. Elucidating the mechanism of PA formation is the basis and premise for preventing its occurrence. In the process of PA formation, a variety of inflammatory cells, inflammatory factors play important roles. In this paper, the mechanism of inflammation and immunoregulatory responses in the formation of adhesions in the peritoneal cavity was reviewed, in order to provide a reference for the improvement of PA prevention strategies.