The early diagnosis and treatment of atypical autoimmune liver disease should be taken seriously
10.3969/j.issn.1001-5256.2022.04.003
- VernacularTitle:重视不典型自身免疫性肝病患者的早诊早治
- Author:
Chunyang HUANG
1
;
Yanmin LIU
1
Author Information
1. Second Department of Liver Disease Center, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
- Publication Type:Discussions by Experts
- Keywords:
Hepatitis, Autoimmune;
Primary Biliary Cholangitis;
Cholangitis, Sclerosing;
Early Diagnosis;
Therapeutics
- From:
Journal of Clinical Hepatology
2022;38(4):748-753
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune liver disease is a group of diseases mainly caused by autoimmune abnormalities, including autoimmune hepatitis dominated by hepatocellular injury, primary biliary cholangitis and primary sclerosing cholangitis dominated by bile duct injury, and overlap syndrome with the main features of the above two diseases. Recently, IgG4-related hepatobiliary diseases have also been included in this category, and without timely diagnosis and treatment, it can progress to liver cirrhosis and even liver failure. Different autoimmune liver diseases have their own features, and with the popularization of the knowledge on autoimmune liver diseases, physicians have gradually increased their understanding of such diseases and can achieve the early diagnosis and timely treatment of most typical autoimmune liver diseases. However, some patients may have atypical manifestations or laboratory markers, which may easily delay the diagnosis, and therefore, it is of great importance to identify atypical autoimmune liver disease and give timely diagnosis and treatment as soon as possible.
