Etiology, diagnosis, and treatment of acute liver failure in neonates
10.3969/j.issn.1001-5256.2022.02.002
- VernacularTitle:新生儿急性肝衰竭的病因、诊断及治疗
- Author:
Xiaomei QIN
1
;
Shuangjie LI
1
Author Information
1. Hunan Provincial Clinical Research Center for Childhood Liver Diseases, Department of Hepatopathy, Hunan Children's Hospital, Changsha 410007, China
- Publication Type:Discussions by Experts
- Keywords:
Liver Failure, Acute;
Diagnosis;
Therapeutics
- From:
Journal of Clinical Hepatology
2022;38(2):260-263
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal acute liver failure is a rare and life-threatening disease in the neonatal period with complete or substantial loss of liver function, and liver cirrhosis can be identified after birth, with a high mortality rate. The main etiologies of this disease include autoimmune liver diseases during pregnancy, viral infection, blood diseases, metabolic diseases, ischemic injury, and other rare causes. At present, etiological treatment is the main treatment method, and liver transplantation is still an important option for patients with unknown etiology or no response to established treatments. Currently there are few studies on neonatal acute liver failure, so prospective studies are needed to investigate the influencing factors for treatment and prognosis.
